Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23405
Gene Symbol: DICER1
DICER1 		0.120 GeneticVariation group BEFREE • DICER1 germline mutations are associated with an inherited cancer syndrome, most commonly pleuropulmonary blastoma, ovarian sex cord tumors, thyroid cysts/goitre, and cystic nephroma. 26526666 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR [The mutations of germline succinate dehydrogrnase subunit B (SDHB) in sporadic paragangliomas]. 21909610 2011
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR [The first molecular analysis of a Hungarian HNPCC family: a novel MSH2 germline mutation]. 15945244 2005
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.150 CausalMutation group CLINVAR [The analysis for mRNA mutation of MLH1, MSH2 genes and the gene diagnosis for hereditary nonpolyposis colorectal cancer]. 16456782 2006
Entrez Id: 4763
Gene Symbol: NF1
NF1 		0.100 CausalMutation group CLINVAR [Phenotypic and genetic features in neurofibromatosis type 1 in children]. 25541118 2015
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.150 CausalMutation group CLINVAR [Mutational analysis of BRCA1 and BRCA2 genes in early-onset breast cancer patients in Shanghai]. 16324400 2005
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		0.110 CausalMutation group CLINVAR [Mutation screening and prenatal diagnosis of tuberous sclerosis complex]. 21811971 2011
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.150 GeneticVariation group CLINVAR [Mutation analysis of hMSH2 and hMLH1 genes in Chinese hereditary nonpolyposis colorectal cancer families]. 14514376 2003
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.150 CausalMutation group CLINVAR [Mutation analysis of hMSH2 and hMLH1 genes in Chinese hereditary nonpolyposis colorectal cancer families]. 14514376 2003
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 GeneticVariation group CLINVAR [Muir-Torre syndrome and familial colorectal cancer: 2 families with molecular genetic analysis]. 10530344 1999
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.170 CausalMutation group CLINVAR [Li Fraumeni syndrome: a case with multiple primary cancers and presenting a germline p53 mutation]. 20478780 2010
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.150 CausalMutation group CLINVAR [Founder mutation in Lynch syndrome]. 27295708 2016
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.150 GeneticVariation group CLINVAR [Detection mutations in the DNA mismatch repair genes of hMLH1 and hMSH2 genes in Colombian families with suspicion of hereditary non-polyposis colorectal carcinoma (Lynch syndrome)]. 16276679 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.170 CausalMutation group CLINVAR [Description of a new TP53 gene germline mutation in a family with the Li-Fraumeni syndrome. Genetic counselling to healthy mutation carriers]. 12406399 2002
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.150 CausalMutation group CLINVAR [Clinical value of screening hereditary nonpolyposis colorectal cancer in China with protocol recommended by NCCN guidelines]. 18636350 2008
Entrez Id: 201163
Gene Symbol: FLCN
FLCN 		0.100 CausalMutation group CLINVAR [Birt-Hogg-Dubé syndrome: an update]. 21937013 2012
Entrez Id: 201163
Gene Symbol: FLCN
FLCN 		0.100 CausalMutation group CLINVAR [Birt-Hogg-Dubé syndrome in a patient with cutaneous symptoms and a c.1429 C > T;p.R477X mutation in exon 12 of the folliculin gene]. 19457309 2009
Entrez Id: 23164
Gene Symbol: MPRIP
MPRIP 		0.100 CausalMutation group CLINVAR [Birt-Hogg-Dubé syndrome in a patient with cutaneous symptoms and a c.1429 C > T;p.R477X mutation in exon 12 of the folliculin gene]. 19457309 2009
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.150 CausalMutation group CLINVAR [Analysis of the mutations of BRCA1 in 9 familiar breast cancer patients]. 12947551 2003
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.150 CausalMutation group CLINVAR [Analysis of mutations in genes BRCA1 and BRCA2 among patients with breast and ovarian cancer in northern Portugal and Galicia]. 12060539 2002
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.130 CausalMutation group CLINVAR [Analysis of BRCA2 gene mutations among familial and/or early-onset breast cancer patients in eastern Shandong of China]. 18393245 2008
Entrez Id: 324
Gene Symbol: APC
APC 		0.110 CausalMutation group CLINVAR [A novel APC gene germline mutation in a familial adenomatous polyposis pedigree]. 16883523 2006
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.150 CausalMutation group CLINVAR [5589del8: the recurrent mutation of BRCA1 gene in Chinese breast cancer patients]. 17680524 2007
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.150 CausalMutation group CLINVAR Younger birth cohort correlates with higher breast and ovarian cancer risk in European BRCA1 mutation carriers. 16287141 2005
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Yield of routine molecular analyses in colorectal cancer patients ≤70 years to detect underlying Lynch syndrome. 22081473 2012